When buying drugs, many customers have faced the fact that in different pharmacies their cost can be very different, and some expensive drugs simply are not available. Nolvadex can be bought without any problems online or in a standard pharmacy. But it is necessary to take into account that if you order online the final purchase amount including payment for delivery is approximately 30% lower than if the customer himself bought the drug at the nearest pharmacy.
Nolvadex is prescribed for the treatment of diseases associated with the mammary gland, a violation of the functionality of the gonads and a violation of erectile function, a favorable cessation of the development of oncological diseases.
The composition of the medicine includes:
- Tamoxifen citrate (main component).
- Magnesium stearate.
- Carboxymethylcellulose calcium.
The drug is available in different dosages with a single component composition.
Form of issue
The medicine is produced in the form of coated tablets. Dosage may differ depending on the amount of tamoxifen citrate present in the tablets.
The primary task of this drug is to prevent the formation of tumors in the body. It helps stop the hypertrophy of cells, stop the synthesis of tumor tissue and completely stop the process of tumor origin.
In other words, Nolvadex protects the body from the onset of oncology. It is worth noting that this drug is not only for women.
If a man has problems with ejaculation (delayed, premature or almost absent), the drug helps to cure this defect, by increasing the concentration of estrogen and testosterone in the blood. For both men and women, the drug is completely safe.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics is almost identical to pharmacological action. The primary activity of the drug is the blocking or destruction of various tumors in the body.
Also, Nolvadex normalizes the work of the female hormonal system, but it also has a beneficial effect on the male body.
The drug restores the functionality of the reproductive system, in case there is a pathology in the form of infertility.
It is due to the elimination of the factor blocking conception and complete normalization of the activity of estrogens.
Nolvadex is easily and quickly absorbed in the stomach (40-50 minutes after ingestion).
One of the main advantages of Nolvadex is the accumulation in the body only in the necessary dose of medication for therapy. The remaining substances are excreted with bile in the form of metabolites.
As mentioned earlier, this drug has a different line of activity with a single specificity. In other words, it blocks the development of cancer cells in different parts of the female body.
Tamoxifen indicated for use:
- Developing breast cancer in menopause (decreased estrogen activity as a result of menopause).
- Complete infertility and impaired erectile function in men. The drug can be useful in the case when it comes to acquired infertility, rather than congenital pathology.
- Endometrial cancer (inner wall of the uterus).
- Prostate cancer (in men).
From all of the above, we can conclude that the main specificity of the drug is the fight against developing cancer cells. With the advanced form of cancer, the medicine can be effective, since it will significantly slow down the destructive effect of the tumor on the body.
Before starting the use of the drug, it is necessary to study in detail the list of contraindications specified in the instructions. Since the drug directly affects not only neoplasms in the body, but also hormones, its use can lead to various negative consequences.
For example, already existing pathologies can become aggravated, a strong allergic reaction to the components of the drug will manifest itself.
Contraindications to taking the medicine are:
- Acute kidney failure.
- Any form of disease of the cardiovascular system.
- Susceptibility to individual components of the drug.
- Any gestation period (especially the first and last few weeks).
- Lactation period.
- In the presence of any disease or brain injury.
- In the presence of diseases of the visual system (cataracts, glaucoma).
Moreover, therapy with Tamoxifen should take place without other hormonal aids. The use of several hormonal drugs at the same time can lead to serious hormonal failures in the body.
Each drug has its own individual effect on the body. In general, side effects are possible complications that may occur after taking the medication.
The list of possible complications:
- Failures in the digestive system: sudden vomiting, loose stool.
- Depression, extremely melancholic mood.
- Nolvadex also affects the visual organ. Perhaps exacerbation of existing diseases or the development of new ones (retinopathy, cataracts).
- Failures in the endocrine system. In women: a sharp increase in weight, internal vaginal bleeding. In men: a complete loss of potency, a lowering of the libido.
- Deterioration of the heart system. Tachycardia, arrhythmia, phlebitis can develop.
- There are various manifestations of the skin: a rash on most parts of the body, hair loss.
- Less common complications include aching in the bones, jumps in body temperature, acute pain in the lesions.
Before the beginning of therapy, it is necessary to undergo a complete examination with specialists and only with their appointment to start using the drug.
Method of administration and dosage
The method of taking and dosage of the drug is practically the same for both men and women.
However, you need to know how to take Nolvadex accurately. The instruction for its use contains all the necessary recommendations, as well as a competently calculated dosage, harmless to health.
Since the beginning of the therapeutic course, the drug is used twice a day, one tablet. Seven days after the start of therapy, the dosage is doubled (two tablets twice a day). The duration of the course of treatment will directly depend on the progression of the disease, as well as the results observed in the patient.
In general, the duration of the course is up to three months, if the main symptomatology is eliminated too slowly. According to the rules of the pill should be washed down with a considerable amount of water. The daily dose is recommended to be divided into two methods: after awakening and before bedtime.